But they resisted all the pressure and worked their way down field, Will Greenwood charging down an attempted drop-goal before England gave away a penalty for handling on the floor that Louis Koen drilled over from wide on the right after 17 minutes
Koen was short with a long-range effort a minute later to emphasise that his side could provide a real contest with unflinching commitment in the tackle.
But England edged in front on the half-hour, though, when Corne Krige broke his binding to come round the wrong side of the scrum with Wilkinson faultless with his second penalty five yards in from the left.
Koen hit the left-hand post with his third penalty attempt a minute later and then failed to hit the target with two more efforts in the 33rd and 35th minutes before finally succeeding a minute before the break with the penalty that levelled the scores.
Straight away after the break England strung together a fantastic series of attacks that ended with South Africa caught offside to give Wilkinson his easiest penalty so far to retake the lead.
Then after halting a stunning Springbok attack they countered when Robinson’s long kick ahead was knocked on setting up the field position from which Wilkinson stroked over the kick that made it 12-6.
The game could still have swung either way as the Boks started to move the ball around with telling knock-ons stopping their most promising efforts.
And the game-changing score came on the hour thanks to the awareness of England’s defence. Lewis Moody – only called in on Friday to take over from Richard Hill – flew in to charge down Koen’s kick and Greenwood followed up to dribble the ball through and score.
Wilkinson converted and polished off another attack with a drop-goal that put his side 16 points clear. For good measure he added another – his seventh successful shot on target – five minutes from time to make it 25-6.
South Africa’s contribution to the game had been huge, but they just couldn’t batter their way over even when they ran a penalty from close-range.
England: Try - Greenwood. Conversion - Wilkinson. Penalties - Wilkinson 4. Drop-goals: Wilkinson 2.