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It will be the first time Bruce Reihana will lead the team out as captain.
Ross Beattie, Geoff Appleford, Simon Emms, Luke Harbut and Brett McNamee will miss the trip due to injury.
Backs: Bruce Reihana (capt), Ben Patston, Sean Lamont*, Ben Cohen, Paul Diggin#, David Quinlan*, Ashley Maggs, Seamus Mallon*, Rhodri Davies, Carlos Spencer*, Luke Myring, Mark Robinson and Ben Jones.
Forwards: Tom Smith, Chris Budgen, Brett Sturgess, Steve Taylor, Dan Richmond, Dylan Hartley#, James Percival*, Matt Lord, Selborne Boome, Damien Browne, Ben Lewitt*, Darren Fox, Mark Easter, Daniel Browne*.
* new player # Academy player
The Treviso game will be followed on Saturday by the Middlesex Sevens at Twickenham. One change has had to be made to the Northampton squad with Julian Bishop coming in for Adam Barnard, who has suffered from dental problems this week.
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