Joe Ewens has been ruled out with a broken toe whilst Anthony Elliott is struggling to shake off glandular fever.
Guy Easterby will captain the side in his first home appearance since his return to the club.
John Pritchard is ruled out with a hamstring problem whilst Mike Umaga has a calf problem. Umaga said:

"I'm suffering a bit at the moment with a bit of a problem with my right calf but i'm hoping to get on top of it this week and play some part at the weekend. The main thing is to get the injury right because if I come back too soon it will keep flaring up and when I'm fit I will train full-time."
Umaga was in the squad that faced Narbonne on Friday and whilst disappointed with the first round exit, admits that the club have to focus primarily on the league:
"We've decided that European rugby is not where we're going to throw all our eggs. The whole thing has to be about surviving the Premiership, that has to be our main priority. I think on Saturday we have to look to get a result and not just a bonus point and with the added experience, I'm sure we can get that."

As far as the new boys are concerned, debuts handed to Brad Macleod-Henderson, Reinier Volschenk, Giscard Pieters and Ryno van der Merwe whilst Corniel van Zyl misses out with flu.